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.:RESEARCH ON HIV/AIDS

 Background Projects
 Objectives Coordinator
  Portfolio   

Background
 
HIV/AIDS is now one major public health issue on a global scale. In the last decade, the use of HAART (highly active antiretroviral therapy) has changed the landscape of the epidemic. The study of HIV pathogenesis has revolutionarised our understanding of virus immunology. Social and behavioural research are continuing to provide new insights of the how’s and why’s of HIV spread.

In Hong Kong, the HIV prevalence is low. The potential risk of HIV dissemination would remain to be with us. There is currently relatively little systematic effort to turn lessons into knowledge, and to generate meaningful research questions that could create impacts. Hong Kong is uniquely positioned to function as a regional hub of HIV research, both because of the early clinical and public health responses to the epidemic, and the track record of reputable scientific research. It is against these backgrounds that an HIV Research Group is formed, under the auspices of the Chinese University Stanley Ho Centre for Emerging Infectious Diseases (CEID).

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Objectives
 
The CEID HIV Research Group (HRG) aims to add value to existing efforts in clinical and public health HIV medicine. Specifically the Group’s objectives are, to:
  • stimulate, promote and support collaborative inter-disciplinary HIV research;
  • coordinate research activities and provide linkage to parallel training and education programmes; and
  • provide a forum to excel in HIV medicine.

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Portfolio
 
The HIV Research group is a focal point in Hong Kong for systematically enhancing academic activities on a common subject – HIV/AIDS.

Four domains are delineated in the initial phase of research development, which are special areas of interest in HIV/AIDS. Domains are constructed on the basis of expertise and interest currently available within the Chinese University. The domains are: epidemiology, social-behavioural science, cohort studies, and clinical science. The specificities and number of domains may change in the course of time.

Epidemiology includes (a) prevalence and incidence studies, (b) molecular epidemiology, and (c) the assessment of factors associated with HIV transmission.

Social-behavioural Science is a set of research activities aiming to innovate and develop models of effective intervention to modify risk behaviours, for the purpose of achieving HIV prevention.

Cohort studies include all experimental work involved in the characterisation of HIV/AIDS patients, their longitudinal monitoring, management of comorbid conditions, mental health, and treatment issues.

Clinical Science focuses on the development of new treatment and investigative tools for enhancing effectiveness in the management of HIV infected patients.

Research activities are organized in specifically defined projects corresponding to any one of the Domains. Research Programme denotes a unified set of research activities bearing a common theme and/or involving the application of a common methodology. In the long run, Programme Leads would be assigned to plan, steer, monitor and evaluate all activities.

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Projects
 
  • Complete genome sequencing of HIV-1 viruses in Hong Kong
  • Potential clinical and economic impact of an outreach healthcare service for prevention of sexually transmitted diseases in Hong Kong
  • Bisexuality and HIV-related risk behaviours among men who have sex with men (MSM) in Hong Kong
  • Prelimonary investigation of the interaction between traditional Chinese medicine (TCM) and CYP450 isoforms
  • The determination of the prevalence of hepatitis C infection in injection drug users in HK
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Coordinator
 

Professor S S Lee
HIV Research Group Coordinator

Stanley Ho Centre for Emerging Infectious Diseases
School of Public Health
The Chinese University of Hong Kong
Prince of Wales Hospital
Shatin, Hong Kong

Tel: 2252 8881
Fax: 2635 4977
Email: sslee@cuhk.edu.hk